The anime Claymore wrapped up with the 26th episode.
I have been watching the fan sub since it first came out and it pretty much followed the manga. Around episode 23 it started diverging. With episode 24 it went totally off the rails with Clare challenging Priscilla.
Naturally the main character wins and ends up sparing the life of the bad guy. It would have been more interesting if they stretched it out into a second season and followed the manga closer. The ending was very anticlimactic; like they ran out of episodes.
Now I just have to see how Darker than Black ends next week.